Profile
Profile
Education and Academic Career???? Prof. Dr. Inga Neumann
| ?Since 2001: | Full professor of Neurobiology & Animal Physiology, Chair of Department of Behavioural & Molecular Neurobiology, University of Regensburg, Germany |
| ?1994-2001: | Senior scientist, Max-Planck-Institute of Psychiatry, Munich, Germany, Behavioural Neuroendocrinology Group |
| ?1996: | Habilitation and venia legendi, Ludwig-Maximilians-University, Munich, Germany |
| ?1992-1994: | ?Postdoctoral student, University of Calgary, Canada, lab Prof. Q. Pittman, PhD |
| ?1992: | PhD in Neurobiology, Dept. of Cell Biology, University of Leipzig, East Germany |
| ?1987-1992: | Scientific assistant (PhD student), Karl-Marx-University of Leipzig, Leipzig |
| ?1987: | Diploma in Biology, Neurobiology, Karl-Marx-University of Leipzig |
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FELLOWSHIPS AND AWARDS
| ?2019: | ?ECNP European Neuropsychopharmacology Award, Kopenhagen |
| ?1997-2001: | ?Heisenberg stipend of the Deutsche Forschungsgemeinschaft |
| ?1994: | ?postdoctoral stipend of the Alberta Heritage Foundation, Canada, 6 months |
| ?1992-94: | ?postdoctoral stipend of the Human Frontier Science Program (HFSPO) |
| ?1992: | ?Award for best PhD thesis, University of Leipzig |
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Academic Services
| 2017-2026: | Director of the DFG Graduate School "Neurobiology of Emotion Dysfunctions" (GRK 2174) at University of Regensburg |
| 2006 -2016: | Organizer & Director of the International Elite-Master-Programme “Experimental and Clinical Neurosciences” at University of Regensburg |
| 10/2017 – 09/2019: | Dean of the Faculty of Biology and Preclinical Medicine, Uni Regensburg |
| 2015-2017: | Vice Dean of the Faculty of Biology and Preclinical Medicine |
| 2013-2015: | Dean for Research, Faculty of Biology and Preclinical Medicine |
| 2012-2016: | Vice Women’s representative of the University of Regensburg |
| Since 2010: | Co-Chair of the Research Initiative “Aggression and Violence in Culture and Nature”; Establishment & Co-Director of the interdisciplinary Master-Programme “Criminology and Aggression Research” at Uni Regensburg |
ORGANISATION OF SCIENTIFIC MEETINGS
| ?2019: | ?Organizer German-Israel MINERVA School “Neurobiology of Socio-Emotional Behaviour” |
| ?2015: | ?Chair of the 1st German Neuropeptide Conference, Regensburg |
| ?2013: | ?Chair of the International Parental Brain Conference, Regensburg |
| ?2007: | ?Chair, 7th World Congress on Neurohypophysial Hormones (WCNH), Regensburg |
Grants
Grants
| 2023 - 2026: | DFG 465/33-2 "Bedeutung des Translokator Proteins (18kDa) (TSPO) als diagnostische und therapeutische Zielstruktur im Nervensystem“ |
| 2022 - 2025: ?? | DFG 462/37 "Die Bedeutung der durch chronische Oxytocin-Gabe induzierten alternativen Splice-Variante des CRF Rezeptor CRFR2α" |
| 2021 - 2024: ? ? ? ? ? ? ? ?? ?? ??????????? | DFG Ne 465/36 “Die Rolle von Endocanabinoiden in der Regulation von sozialer Angst“ |
| 2019 - 2022: | DFG Ne 465/34 “Neuronale Mechanismen der sozialen Angstkonditionierung in der Maus“ |
| 2019 – 2022: | DFG Ne465/33 ?Bedeutung des Translokator-Proteins 18kDa TSPO als diagnostische und therapeutische Zielstruktur im Nervensystem“ |
| 2018 – 2021: | DFG Ne 465/31 “Effects of acute and chronic oxytocin activation on intraneuronal signaling cascades” |
| 2017 – 2021: | DFG Graduate programme “Neurobiology of Emotion Dysfunctions” (GRK 2174) - prolongation until 2026 |
| 2014-2018: | DFG Ne 465/27-1 (1 PhD, 1 technician + 64.000) � “Chronic oxytocin and NPS administration” |
| 2015-2018: | BMBF-Verbund (Joint research project) “OptiMD” within research network for mental diseases: Identification and Validation of new target structures of the brain for anti-depressive medication in animal models” (SP1) |
| 2013-2018: | 7th FP EU; FemNat CD (Neurobiology of female conduct disorder; 315.000 �) |
| 2006 – 2016: | Elitenetwork Bavaria: Elite Masterprogramme “Experimental and Clinical Neuroscience” |
| 2012-2016: | DFG Ne 465/16-2 (1 PhD, 1 technician + 89.000 �) “Effects of chronic stress in pregnancy on hypothalamic gene expression patterns” |
| 2011-2014: | DFG (1 postdoc + 75.000) “Intracellular actions of oxytocin: link to anxiolysis” |
| 2008-2011/15: | DFG (1TA, 1PhD student + 76.000 �), “Stress adaptations in pregnancy” |
| 2006-2012: | DFG (1TA, 2 PhD, + 85.000�), “Chronic stress and colitis” |
| 2009-2012: | DFG (1 postdoc, 1 PhD + 63.000 �), “Neurobiology of aggression” |
| 2008-2011: | BMBF-Verbund (Joint research project) “Oxytocin and social behaviour” |
| 2008-2011: | Bavarian Research Foundation (68.000 �) “Sexual activity and anxiolysis” |
| 2010-2012: | Bavarian Research Foundation (72.000 �) “Oxytocin actions in social fear conditioning” |
| 2013-2015: | Bavarian Research Foundation (72.000 �) “Epigenetic mechanisms of oxytocin actions in fear conditioning” |
| 2001-2007: | Volkswagenstiftung (473.000 �), “Prenatal stress, anxiety and neurogenesis” |
| DAAD - SFN: | With Prof. Larry Young, Emory University, Atlanta, 2004-2006 |
| DAAD - UK: | With Prof. John Russell, University of Edinburgh, 2008-2010 |
| DAAD - Australia: | With Prof. Iain McGregor, University of Sydney, 2011-2013 |
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Publications
Publications
List of publications 2006-2024 ???????????????????????????????????????? Prof. Dr. Inga D. Neumann
(1)?? Peer-reviewed papers
2024
Grossmann CP, Sommer C, Fahliogullari IF, Neumann ID, Menon R. Mating-induced release of oxytocin in the mouse lateral septum: Implications for soical fear extinction: Psychoneuroendocrinology 2024;166:107083.doi:10.1016/j.psyneuen.2024.107083.
2023
Neumann ID, Menon R. Detection, processing, and reinforcement of social cues: regulation by the oxytocin system. Nat Rev Neurosci. 2023;doi:10.1038/s41583-023-00759-w. Online ahead of print
Neumann ID. Monitoring oxytocin signaling in the brain: more than a love story. Compr. Psychoneuroendocrinology 2023;(16)100206.??
Pandamooz S, Salehi MS, Jurek B, Meinung CP, Azarpira N, Dianatpour M, Neumann ID.Oxytocin Receptor Expression in Hair Follicle Stem Cells: A Promising Model for Biological and Therapeutic Discovery in Neuropsychiatric Disorders. Stem Cell Rev Rep 2023;doi: 10.1007/s12015-023-10603-4. Online ahead of print.
Tabak BA, Leng G, Parker KJ, Verbarlis JG, Ziegler TE, Lee MR, Neumann ID, Mende AJ. Advances in human oxytocin measurement: challenges and proposed solutions. Mol Psych 2023;28(1):127-140. ????
Bludau A, Neumann ID, Menon R. HDAC1-mediated regulation of GABA signaling within the lateral septum facilitates long-lasting social fear extinction in male mice. Transl Psychiatry 2023;13:10 ; https://doi.org/10.1038/s41398-023-02310-y.
Gryksa K, Schmidtner AK, Masís-Calvo M, Rodríguez-Villagra OA, Havasi A, Wirobski G, Maloumby R, J?gle H, Bosch OJ, Slattery DA, Neumann ID. Selective breeding of rats for high (HAB) and low (LAB) anxiety-related behaviour: A unique model for comorbid depression and social dysfunctions. Neurosci Biobehav Rev 2023;152:105292. doi: 10.1016/j.neubiorev.2023.105292.
2022
Oliveira VEM, de Jong TR, Neumann ID. Syntetic Oxytocin and Vasopressin act within the central Amygdala to exacerbate agression in female wistar rats. Front Neurosci 2022;16:906617.
Leschik J, Gentile A, Cicek C, Péron S, Tevosian M, Beer A, Radyushkin K, Bludau A, Ebner K, Neumann ID, Singewald N, Berninger B, Lessmann V, Lutz B. Brain-derived neurotrophic factor expression in serotonergic neurons improves stress resilience and promotes adult hippocampal neurogenesis. Prog Neurobiol 2022;217:102333.
Cohen AJ, Neumann ID. A model for the social neurscience of music productions begins on a dubious note: Commentary on Greenberg et al. Am Psychol 2022;(4)616-18.
Rupprecht R, Wetzel CH, Dorostkar M, Herms J, Albert NL, Schwarzbach J, Schumacher M, Neumann ID. Translocator protein (18kDa) TSPO: a new diagnostic or therapeutic target for stress-related disorders? Review Mol Psychiatry 2022;27(7):2918-2926.
Royer M, Pai B, Menon R, Bludau A, Gryksa K, Perry RB, Ulitsky I, Meister G, Neumann ID. Transcriptome and chromatin alterations in social fear indicate association of MEG3 with successful fear extinction. Mol Psych 2022;27(10): 4064–4076.
Meyer M, Jurek B, Alfonso-Prieto M, Ribeiro R, Milenkovic VM, Winter J, Hoffmann P, Wetzel CH, Giorgetti A, Carloni P, Neumann ID. Structure-function relationships of the disease-linked A218T oxytocin receptor variant. Mol Psychiatry 2022; 27(2);907-917.
Gryksa K, Neumann ID. Consequences of pandemic-associated social restrictions: Role of social support and the oxytocin system. Psychoneuroendocrinology 2022;135:105601.
Carboni L, El Khoury A, Beiderbeck DI, Neumann ID, Mathé AA. Neuropeptide Y, calcitonin gene-related peptide, and neurokinin A in brain regions of HAB rats correlate with anxiety-like behaviours. Eur Neuropsychopharmacol 2022;7;57:1-14.
Menon R, Suess T, Oliveira VEM, Neumann ID, Bludau A. Neurobiology of the lateral septum: regulation of social behavior. Trends Neurosci 2022; 45(1):27-40.
2021
Winter J, Meyer M, Berger I, Royer M, Bianchi M, M. Sc., Kuffner K, Peters S, Stang S, Langgartner D, Hartmann F, Schmidtner AK, Reber SO, Bosch OJ, Bludau A, Slattery DA, van den Burg E, Jurek B, Neumann ID (2021). Chronic oxytocin-driven alternative splicing of CRFR2α induces anxiety. Mol Psychiatry 2021;?doi:10.1038/s41380-021-01141-x. ??
Oliveira VEM, Lukas M, Wolf HN, Durante E, Lorenz A, Mayer AL, Bludau A, Bosch O, Grinevich V, Egger V, de Jong TR, Neumann ?ID (2021) Oxytocin and vasopressin within the ventral and dorsal lateral septum modulate aggression in female rats. Nat Commun 2021;12(1):2900.
Albantakisa L, Brandia ML, Brückl T, Gebert D, Auer MK, Kopczak A, Stalla GK, Neumann ID, Schilbach L. Oxytocin and cortisol concentrations in adults with and without autismspectrum disorder in response to physical exercise. Psychoneuroendocrinology 2021;(5)100027.
2020
Malik VA, Zajicek F,? Mittmann LA, Klaus J, Unterseer S, Rajkumar S, Pütz B, Deussing JM, Neumann ID, Rupprecht R, Di Benedetto B. GDF15 promotes simultaneous astrocyte remodeling and tight junction strengthening at the blood-brain barrier. J Neurosci Res.;doi: 10.1002/jnr.24611
Tang Y, Benusiglio D, Lefevre A, Hilfiger L, Althammer F, Bludau A, Hagiwara D, Baudon A, Schimmer J, Kirchner MK, Roy RK, WangvS, Eliava M, Wagner S, Conzelmann KK, Schwarz M, Stern JE, Leng G, Charlet A, Grinevich V, Neumann ID. Social touch promotes inter-female communication via oxytocin parvocellular neurons. Nat Neurosci 2020;(9):1125-1137.
Grinevich V, Neumann ID. Brain oxytocin: how puzzle stones from animal studies translate into psychiatry. Mol Psychiatry 2020;1-15.
Meyer M, Kuffner K, Winter J, Neumann ID, Wetzel CH, Jurek B. Myocyte Enhancer Factor 2A (MEF2A) Defines Oxytocin-Induced Morphological Effects and Regulates Mitochondrial Function in Neurons. Int J Mol Sci. 2020;21(6):2200.
Anpilov S, Shemesh Y, Eren N, Harony-Nicolas H, Benjamin A, Dine J, Oliveira VEM, Forkosh O, Karamihalev S, Hüttl RE, Feldman N, Berger R, Dagan A , Chen G, Neumann ID, Wagner S, Yizhar O, Chen A. Wireless Optogenetic Stimulation of Oxytocin Neurons in a Semi-natural Setup Dynamically Elevates Both Pro-social and Agonistic Behaviors. Neuron. 2020;107(4):644-655.e7.
Zoicas I, Mühle C, Schmidtner AK, Gulbins E, Neumann ID, Kornhuber J. Anxiety and Depression Are Related to Higher Activity of Sphingolipid Metabolizing Enzymes in the Rat Brain. Cells 2020;9(5):E1239.
2019
Schmidtner AK, Slattery DA, Gl?sner J, Hiergeist A, Gryksa K, Malik VA, Hellmann-Regen J, Heuser I, Baghai TC, Gessner A, Rupprecht R, Di Benedetto B, Neumann ID. Minocycline alters behavior, microglia and the gut microbiome in a trait-anxiety-dependent manner. Transl Psychiatry;9(1):223
Martinetz S, Meinung CP, Jurek B, von Schack D, von den Burg EH, Slattery DA, Neumann ID. De Novo protein synthesis mediated by the eukaryotic elongation factor 2 is required for the anxiolytic effect of oxytocin. Biol Psychiatry;85(10):802-11
Grund T, Tang Y, Benusiglio D, Althammer F, Probst S, Oppenl?nder L, Neumann ID, Grinevich V. Chemogentic activation of oxytocin neurons:?Temporal dynamics, hormonal release and behavioral consequences. Psychoneuroendocrinology;106:77-84
Bludau A, Royer M, Meister G, Neumann ID, Menon R. Epigenetic regulation of the social brain. J Neurosci; Review
Neumann ID, Landgraf R. Tracking oxytocin functions in the rodent brain during the last 30 years: From push-pull perfusion to chemogenetic silencing. J Neuroendocrinology;(3)e12695.soi:10.1111/jne.12695
Oliveira VEM, Neumann ID, de Jong TR. Post-weaning isolation exacerbates aggression in both sexes and affects the vasopressin and oxytocin system in a sex-specific manner. Neuropharmacology;doi:10.1016/j.neuropharm.2019.01.019 (epub ahead of print)
Grund T, Neumann ID. Brain neuropeptide S:?Via GPCR activation to a powerful neuromodulator of socio-emotional behaviors. Cell Tissue Res;375(1):123-32
2018
Menon R, Grund T, Zoicas I, Althammer F, Fiedler D, Biermeier V, Bosch OJ, Hiraoka Y, Nishimori K, Eliava M, Grinevich V, Neumann ID. Oxytocin signalling in the lateral septum prevents social fear during lactation. Curr Biol
Jurek B, Neumann ID. The Oxytocin Receptor:?From Intracellular signalling to behavior:?Physiol Rev. 98 (3):1805-08
Masís-Calvo M, Schmidtner AK, de Moura Oliveira VE, Grossmann CP, de Jong TR, Neumann ID. Animal models of social stress: the dark side of social interactions. Stress;21(5)417-32 1-16
Bowen MT, Neumann ID. Mulitdimensional therapeutic potential of targeting the brain oxytocin system for the treatment of substance use disorders. Curr Top Behav Neurosci. 35:269-87
Bernhard A, van der Merwe C, Ackermann K, Martinelli A, Neumann ID, Freitag CM. Adolescent oxytocin response to stress and its behavioral and endocrine correlates. Horm Behav;105:157-65
Grund T, Neumann ID. Brain neuropeptide S:?via GPCR activation to a powerful neuromodulator of socio-emotional behaviors. Cell Tissue Res;43(5):1156-63
Bosch OJ, Pohl TT, Neumann ID, Young LJ. Abandoned prairie vole mothers show normal maternal care but altered emotionality: Potential influence of the brain corticotropin-releasing factor system. Behav Brain Res.; 341:114-121
de Jong TR, Neumann ID. Oxytocin and Aggression. Curr Top Behav Neurosci. 35:175-92
Grund T, Neumann ID. Neuropeptide S Induces Acute Anxiolysis by Phospholipase C-Dependent Signaling within the Medial Amygdala. Neuropsychopharmacology 43(5):1156-63.
2017
Muttenthaler M, Andersson ?, Vetter I, Menon R, Busnelli M, Ragnarsson L, Bergmayr C, Arrowsmith S, Deuis JR, Chiu HS, Palpant NJ, O'Brien M, Smith TJ, Wray S, Neumann ID, Gruber CW, Lewis RJ, Alewood PF. Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species. Sci Signal.;10(508).
Bowen MT, Neumann ID. Rebalancing the addicted brain: Oxytocin interference with the neuronal substrates of addiction. Trends Neurosci.40(12):691-708
Grund T, Goyon S, Li Y, Eliava M, Liu H, Charlet A, Grinevich V, Neumann ID. Neuropeptide S activates paraventricular oxytocin neurons to induce anxiolysis. J Neurosci.; 37:12214-12225
Schladt TM, Nordmann GC, Emilius R, Kudielka BM, de Jong TR, Neumann ID. Choir versus solo singing: effects on mood, and salivary oxytocin and cortisol concentrations. Front Hum Neurosci. 14;11:430
Bowen MT, Neumann ID. The multidimensional therapeutic potential of targeting the brain oxytocin system for the treatment of substance use disorders. Curr Top Behav Neurosci. 10.1007/7854_2017_17
de Jong TR, Neumann ID. Oxytocin and Aggression. Curr Top Behav Neurosci. doi:10.1007/7854_2017_13
Grund T, Neumann ID. Neuropeptide S induces acute anxiolysis by phospholipase c-dependent signaling within the medial amygdala. Neurospychopharmacology. doi: 10.1038/npp.2017.169
Torner L, Plotsky PM, Neumann ID, de Jong TR. Corrigendum to "Forced swimming-induced oxytocin release into blood and brain: Effects of adrenalectomy and corticosterone treatment". Psychoneuroendocrinology; 85:218
Torner L, Plotsky PM, Neumann ID, de Jong TR. Forced swimming-induced oxytocin release into blood and brain: Effects of adrenalectomy and corticosterone treatment. Psychoneuroendocrinology; 77:165-74
Peters ST, Bowen MT, Bohrer K, McGregor IS, Neumann ID. Oxytocin inhibits ehtanol consumption and ethanol-induced dopamine release in the nucleus accumbens. Addict Biol.;22(3):702-711
Slattery DA, Neumann ID, Flor PJ, Zoicas I. Pharmacological modulation of metatropic glutamate receptor subtype 5 and 7 impairs extinction of social fear in a time-point-dependant manner. Behav Brain Res.;328:57-61
Perani CV, Langgartner D, Uschold-Schmidt N, Füchsl AM, Neumann ID, Reber SO, Slattery DA. Adrenal gland plasticity in lactating rats and mice is sufficient to maintain basal hypersecretion of corticosterone. Stress;3:303-311
2016
Sartori SB, Maurer V, Murphy C, Schmuckermair C, Muigg P, Neumann ID, Whittle N, Singewald N. Combined Neuropeptide S and D-Cycloserine augmentation prevents the return of fear in extinction-impaired rodents: advantage of dual versus single drug approaches. Int J Neuropsychopharmacol.; 19(06)
Carnevali L, Andrews PL, Neumann ID, Nalivaiko E, Sgoifo A. Autonomic changes induced by provocative motion in rats bred for high (HAB) and low (LAB) anxiety-related behavior: paradoxical responses in LAB animals. Physiol Behav.;167:363-73
Zoicas I, Menon R, Neumann ID. Neuropeptide S reduced fear and avoidance of con-specifics induced by social fear conditioning and social fear defeat, respectively. Neuropharmacology; 108:284-91
Bosch OJ, Dabrowska J, Modi ME, Johnson ZV, Keebaugh AC, Barrett CE, Ahem TH, Guo J, Grinevich V, Rainnie DG, Neumann ID, Young LJ. Oxytocin in the nucleus accumbens shell reverses CRFR2-evoked passive stress-coping after partner loss in monogamous male prairie voles. Psychoneuroendocrinology; 64:66-78
Martinetz S, Neumann ID. The potential of osytocin as a therapeutic target for psychiatric disorders. Expert Opin Ther Targets; 20:515-8
Bayerl DS, Kaczmarek V, Jurek B, van den Burg EH, Neumann ID, Ga?ner BM, Klampfl SM, Bosch OJ. Antagonism ov V1b receptors promotes maternal motivation to retrieve pups in the MPOA and impairs pup-directed behavior during maternal defens in the mpBNST of lactating rats. Horm Behav.; 79:18-27
Di Benedetto B, Malik VA, Begum S, Jablonowski L, Gómez-Gonzáles GB, Neumann ID, Rupprecht R. Fluoxetine requires the endfeet protein aquporin-4 to enhance plasticity of astrocyte processes. Front Cell Neurosci.; 10:8
Zoicas I, Neumann ID. Maternal separation facilitates extinction of social fear in adult male mice. Behav Brain Res.; 297:323-8
Neumann ID, Slattery DA. Oxytocin in general anxiety and social fear: A translational approach. Biol Psychiatry; 79(3):213-21
2015
Perani CV, Neumann ID, Reber SO, Slattery DA. High-fat diet prevents adaptive peripartum-associated adrenal gland plasticity and anxiolysis. Sci Rep. 7;5:14821.
Jong TR, Menon R, Bludau A, Grund T, Biermeier V, Klampfl SM, Jurek B, Bosch OJ, Hellhammer J, Neumann ID. Salivary oxytocin concentrations in response to running, sexual self-stimulation, breastfeeding and the TSST: The Regensburg Oxytocin Challenge (ROC) study. Psychoneuroendocrinology ;62:381-8.
Carnevali L, Vacondio F, Rossi S, Macchi E, Spadoni G, Bedini A, Neumann ID, Rivara S, Mor M, Sgoifo A. Cardioprotective effects of fatty acid amide hydrolase inhibitor URB694, in a rodent model of trait anxiety. Sci Rep.;5:18218.
Bernhard A, Martinelli A, Ackermann K, Neumann ID, Kirschbaum C, Freitag CM. Reactivity of oxytocin in the Trier Social Stress Test: A proof of concept study.Psychoneuroendocrinology;61:73.
Frijling JL, van Zuiden M, Nawijn L, Koch SB, Neumann ID, Veltman DJ, Olff M. Salivary oxytocin and vasopressin levels in police officers with and without post-traumatic stress disorder. J Neuroendocrinol.; 27:743-51.
van den Burg EH, Stindl J, Grund T, Neumann ID, Strauss O. Oxytocin Stimulates Extracellular Ca2+ Influx Through TRPV2 Channels in Hypothalamic Neurons to Exert its Anxiolytic Effects. Neuropsychopharmacology; 40:2938-47
Shiban Y, Reichenberger J, Neumann ID, Mühlberger A. Social conditioning and extinction paradigm: a translational study in virtual reality. Front Psychol.;6:400
Slattery DA, Naik RR, Grund T, Yen YC, Sartori SB, Fuechsl A, Finger BC, Elfving B, Nordemann U, Guerrini R, Calo G, Wegener G, Math AA, Singewald N, Czibere L, Landgraf L, Neumann ID. Selective breeding for high anxiety introduces a synonymous SNP that increases neuropeptide S receptor activity. J Neurosci.; 35:4599-613
Jurek B, Slattery DA, Hiraoka Y, Liu Y, Nishimori K, Aguilera G , Neumann ID, van den Burg EH. Oxytocin regulates stress-induced CRF gene transcription through CREB-regulated transcription coactivator 3 (CRTC3). J Neurosci.;35:12248-60
Bowen MT, Peters ST, Absalom N, Chebib M, Neumann ID, McGregor IS. Oxytocin prevents ethanol actions at δ subunit-containing GABAA receptors and attenuates ethanol-induced motor impairment in rats. Proc Natl Acad Sci U S A.;112:3104-9
de Jong TR, Neumann ID. Moderate Role of Oxytocin in the Pro-Ejaculatory Effect of the 5-HT1A Receptor Agonist 8-OH-DPAT. J Sex Med.;12:17-28
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?2014
Bosch OJ, Slattery DA, Neumann ID. The 5th parental brain conference. J Neuroendocrinol;625-6
Lonstein JS, Maguire J, Meinlschmidt G, Neumann ID. Emotion and Mood Adaptations in the Peripartum Female: Complementary Contributions of GABA and Oxytocin. J Neuroendocrinol;649-64.
Haller J, Harold G, Sandi C, Neumann ID. Effects of adverse early-life events on aggression and anti-social behaviours in animals and humans. J Neuroendocrinol;724-38
Beiderbeck DI, Lukas M, Neumann ID. Anti-aggressive effects of neuropeptide S independent of anxiolysis in male rats. Front Behav Neurosci.;30;8:185. eCollection 2014.
Zoicas I, Slattery DA, Neumann ID. Brain Oxytocin in Social Fear Conditioning and its Extinction: Involvement of the Lateral Septum. Neuropsychopharmacology;39(13):3027-35
Zamorano M, Ledesma-Colunga MG, Adán N, Vera-Massieu C, Lemini M, Méndez I, Moreno-Carranza B, Neumann ID, Thebault S, Martínez de la Escalera G, Torner L, Clapp C. Prolactin-derived vasoinhibins increase anxiety- and depression-related behaviors. Psychoneuroendocrinology;44:123-32
de Jong TR, Beiderbeck DI, Neumann ID. Measuring virgin female aggression in the female intruder test (FIT): effects of oxytocin, estrous cycle, and anxiety. PLoS One;9(3):e91701
Lukas M, Neumann ID. Social preference and maternal defeat-induced social avoidance in virgin female rats: Sex differences in involvement of brain oxytocin and vasopressin. J Neurosci Methods;234:101-7
Calcagnoli F, de Boer SF, Beiderbeck DI, Althaus M, Koolhaas JM, Neumann ID. Local oxytocin expression and oxytocin receptor binding in the male rat brain is associated with aggressiveness. Behav Brain Res;15;261:315-22
Füchsl AM, Neumann ID, Reber SO. Stress resilience-a low-anxiety genotype protects male mice from the consequences of chronic psychosocial stress. Endocrinology;155(1):117-26
Peters S, Slattery DA, Uschold-Schmidt N, Reber SO, Neumann ID. Dose-dependent effects of chronic central infusion of oxytocin on anxiety, oxytocin receptor binding and stress-related parameters in mice. Psychoneuroendocrinology; 42,225—236
Carnevali L, Trombini M, Graiani G, Madeddu D, Quaini F, Landgraf R, Neumann ID, Nalivaiko E, Sgoifo A. Low vagally-mediated heart rate variability and increased susceptibility to ventricular arrhythmias in rats bred for high anxiety. Physiol Behav;128;16-25
Hillerer KM, Neumann ID, Couillard-Despres S, Aigner L, Slattery DA. Lactation-induced reduction in hippocampal neurogenesis is reversed by repeated stress exposure. Hippocampus;6;673-83
Forkwa TK, Neumann ID, Tamm ER, Ohlmann A, Reber SO. Short-term psychosocial stress protects photoreceptors from damage via corticosterone-mediated activation of the AKT pathway. Exp Neurol;252:28-36
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2013
Lukas M, Neumann ID. Oxytocin and vasopressin in rodent behaviors related to social dysfunctions in autism spectrum disorders. Behav Brain Res;15;251:85-94.
Czech B, Neumann ID, Müller M, Reber SO, Hellerbrand C. Effect of chronic psychosocial stress on nonalcoholic steatohepatitis in mice. Int J Clin Exp Pathol;15;6(8):1585-93
Toth I, Neumann ID. Animal models of social avoidance and social fear. Cell Tissue Res; 354(1):107-18
Klampfl SM, Neumann ID, Bosch OJ. Reduced brain corticotropin-releasing factor receptor activation is required for adequate maternal care and maternal aggression in lactating rats. Eur J Neurosci; 38(5):2742-50
Peters S, Slattery DA, Flor PJ, Neumann ID, Reber SO. Differential effects of baclofen and oxytocin on the increased ethanol consumption following chronic psychosocial stress in mice. Addict Biol;18:66-77
Carnevali L, Sgoifo A, Trombini M, Landgraf R, Neumann ID, Nalivaiko E. Different patterns of respiration in rat lines selectively bred for high or low anxiety. PLoS One; 17;8(5): e64519
Neumann ID, Maloumby R, Beiderbeck DI, Lukas M, Landgraf R. Increased brain and plasma oxytocin after nasal and peripheral administration in rats and mice. Psychoneuroendocrinology; 38(10):1985-93
Toth I, Neumann ID, Slattery DA. Social fear conditioning as an animal model of social anxiety disorder. Curr Protoc Neurosci;Chapter 9;Unit 9.42.
Hillerer KM, Neumann ID, Couillard-Despres S, Aigner L, Slattery DA. Sex-dependent regulation of hippocampal neurogenesis under basal and chronic stress conditions in rats. Hippocampus; 23(6):476-87.
Bertsch K, Schmidinger I, Neumann ID, Herpertz SC. Reduced plasma oxytocin levels in female patients with borderline personality disorder. Horm Behav; 63(3):424-9
Lukas M, Toth I, Veenema AH, Neumann ID. Oxytocin mediates rodent social memory within the lateral septum and the medial amygdala depending on the relevance of the social stimulus: Male juvenile versus female adult conspecifics. Psychoneuroendocrinology; 38(6):916-26
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2012
Nyuyki KD, Beiderbeck DI, Lukas M, Neumann ID, Reber SO. Chronic Subordinate Colony Housing (CSC) as a Model of Chronic Psychosocial Stress in Male Rats. PLoS One;7(12):e52371.
Bartlang MS, Neumann ID, Slattery DA, Uschold-Schmidt N, Kraus D, Helfrich-F?rster C, Reber SO. Time matters: pathological effects of repeated psychosocial stress during the active, but not inactive, phase of male mice. J Endocrinol;15(3):425-37.
Jurek B, Slattery DA, Maloumby R, Hillerer K, Koszinowski S, Neumann ID, van den Burg EH. Differential contribution of hypothalamic MAPK activity to anxiety-like behaviour in virgin and lactating rats. PLoS One;7(5):e37060
Okimoto N, Bosch OJ, Slattery DA, Pflaum K, Matsushita H, Wei FY, Ohmori M, Nishiki T, Ohmori I, Hiramatsu Y, Matsui H, Neumann ID, Tomizawa K. RGS2 mediates the anxiolytic effect of oxytocin. Brain Res; 1453:26-33.
Neumann ID, Landgraf R. The brain oxytocin and vasopressin systems in anxiety and depression: Link to Sociality. Trends in Neurosciences;35(11):649-659
Beiderbeck D, Reber SO, Havasi A, Veenema A, Neumann ID. High and abnormal forms of aggression in rats with extremes in trait anxiety – involvement of the dopamine system in the nucleus accumbens. Psychoneuroendocrinology ;37(12):1969-80.
Toth I, Neumann ID, Slattery DA. Central administration of oxytocin receptor ligands affects cued fear extinction in rats and mice in a timepoint-dependent manner. Psychopharmacology ; 223(2):149-58
Toth I, Neumann ID, Slattery DA. Social fear conditioning - a novel and specific animal model to study social anxiety disorder. Neuropsychopharmacology ; 37(6):1433-43
Slattery DA, Uschold N, Magoni? M, Baer J, Popoli M, Neumann ID, Reber SO. Behavioural consequences of two chronic psychosocial stress paradigms: anxiety without depression. Psychoneuroendocrinology ; 37(5) ;702-14
Lukas M, Neumann ID. Nasal application of neuropeptide S reduces anxiety and prolongs memory in rats: Social versus non-social effects. Neuropharmacology ;62(1);398-405
Nyuyki KD, Maloumby R, Reber SO, Neumann ID. Comparison of corticosterone responses to acute stressors: chronic jugular vein versus trunk blood samples in mice. Stress;15(6);618-26
Peters S, Grunwald N, Rümmele N, Endlicher E, Lechner A, Obermeier F, Reber SO. Chronic psychosocial stress increases the risk for inflammation-related colon cancerogenesis in male mice. Stress;15(4);403-15
Toth I, Dietz M, Fendt M, Neumann, ID, Flor P, Slattery D. Pharmacological interference with metabotropic glutamate receptor subtype 7 but not subtype 5 differentially affects within- and between-session extinction of Pavlovian conditioned fear. Neuropharmacology ;62;1619-26
Uschold-Schmidt N, Nyuyki KD, Füchsl AM, Neumann ID, Reber SO. Chronic psychosocial stress results in sensitization of the HPA axis to acute heterotypic stressors despite a reduction of adrenal in vitro ACTH responsiveness. Psychoneuroendocrinology ; 37(10) ;1676-87.
Wegener G, Mathe AA, Neumann ID. Selectively bred rodents as models of depression and anxiety. Curr Top Behav Neurosci ;12;139-87.
Bosch OJ, Neumann ID. Both oxytocin and vasopressin are mediators of maternal care and aggression in rodents: from central release to sites of action. Horm Behav ;61(3):293-303.
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2011
Jurek B, Slattery DA, Maloumby R, Hillerer K, Brockmann M, Neumann ID, vd Burg E. The MAPK signalling pathway within the hypothalamic PVN is critically involved in both lactation- and oxytocin-induced anxiolysis: pharmacological evidence. Endocrinology ;152(10);3930-40
Hillerer KM, Reber SO, Neumann ID, Slattery DA. Exposure to chronic pregnancy stress reverses peripartum associated adaptations: implications for post-partum anxiety and mood disorders. Endocrinology;152; 3930-40
Nyuyki K, Waldherr M, B?uml, S, Neumann ID. Yes, I Am ready now: Differential effects of paced versus unpaced mating on anxiety and central oxytocin release in female rats. PloS One;6(8);e23599
Lukas M, Toth I, Reber SO, Slattery DA, Veenema AH, Neumann ID. The neuropeptide oxytocin facilitates pro-social behavior and prevents social avoidance in rats and mice. Neuropsychopharmacology; 36;2159-68
Lukas M, Bredewold R, Landgraf R, Neumann ID, Veenema AH. Early life stress impairs social recognition due to a blunted response of vasopressin release within the septum of adult male rats. Psychoneuroendocrinology; 36(6);843-853.
Reber SO, Peters S, Slattery DA, Hofmann C, Sch?lmerich J, Neumann ID, Obermeier F. Mucosal immunosuppression and epithelial barrier defects are key events in murine psychosocial stress-induced colitis. Brain Behav Immun; 25(6);1153-1161
Wegener G, Finger BC, Elfving B, Keller K, Liebenberg N, Fischer CW, Singewald N, Slattery DA, Neumann ID, Mathé AA. Neuropeptide S alters anxiety, but not depression-like behaviour in